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Role of EscU auto-cleavage in promoting type III effector translocation into host cells by enteropathogenic Escherichia coli

BACKGROUND: Type III secretion systems (T3SS) of bacterial pathogens coordinate effector protein injection into eukaryotic cells. The YscU/FlhB group of proteins comprises members associated with T3SS which undergo a specific auto-cleavage event at a conserved NPTH amino acid sequence. The crystal s...

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Detalles Bibliográficos
Autores principales: Thomassin, Jenny-Lee, He, Xiang, Thomas, Nikhil A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189125/
https://www.ncbi.nlm.nih.gov/pubmed/21933418
http://dx.doi.org/10.1186/1471-2180-11-205