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Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2

BACKGROUND: Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanisms are regulated within bone marrow stromal cell (BMSC) microenvironment remain...

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Detalles Bibliográficos
Autores principales: Valcárcel, María, Mendoza, Lorea, Hernández, José-Julio, Carrascal, Teresa, Salado, Clarisa, Crende, Olatz, Vidal-Vanaclocha, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189126/
https://www.ncbi.nlm.nih.gov/pubmed/21867538
http://dx.doi.org/10.1186/1479-5876-9-142