Binding-Folding Induced Regulation of AF1 Transactivation Domain of the Glucocorticoid Receptor by a Cofactor That Binds to Its DNA Binding Domain

Intrinsically disordered (ID) regions of proteins commonly exist within transcription factors, including the N-terminal domain (NTD) of steroid hormone receptors (SHRs) that possesses a powerful activation function, AF1 region. The mechanisms by which SHRs pass signals from a steroid hormone to cont...

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Detalles Bibliográficos
Autores principales: Garza, Anna S., Khan, Shagufta H., Moure, Carmen M., Edwards, Dean P., Kumar, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189220/
https://www.ncbi.nlm.nih.gov/pubmed/22003412
http://dx.doi.org/10.1371/journal.pone.0025875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189220/
https://www.ncbi.nlm.nih.gov/pubmed/22003412
http://dx.doi.org/10.1371/journal.pone.0025875

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