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Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development
Interferon regulatory factor (IRF) 8 and IRF4 are structurally-related, hematopoietic cell-specific transcription factors that cooperatively regulate the differentiation of dendritic cells and B cells. Whilst in myeloid cells IRF8 is known to modulate growth and differentiation, the role of IRF4 is...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189223/ https://www.ncbi.nlm.nih.gov/pubmed/22003407 http://dx.doi.org/10.1371/journal.pone.0025812 |