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Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development

Interferon regulatory factor (IRF) 8 and IRF4 are structurally-related, hematopoietic cell-specific transcription factors that cooperatively regulate the differentiation of dendritic cells and B cells. Whilst in myeloid cells IRF8 is known to modulate growth and differentiation, the role of IRF4 is...

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Detalles Bibliográficos
Autores principales: Yamamoto, Michio, Kato, Takayuki, Hotta, Chie, Nishiyama, Akira, Kurotaki, Daisuke, Yoshinari, Masahiro, Takami, Masamichi, Ichino, Motohide, Nakazawa, Masatoshi, Matsuyama, Toshifumi, Kamijo, Ryutaro, Kitagawa, Seiichi, Ozato, Keiko, Tamura, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189223/
https://www.ncbi.nlm.nih.gov/pubmed/22003407
http://dx.doi.org/10.1371/journal.pone.0025812