Elevated Global SUMOylation in Ubc9 Transgenic Mice Protects Their Brains against Focal Cerebral Ischemic Damage

We have previously shown that a massive increase in global SUMOylation occurs during torpor in ground squirrels, and that overexpression of Ubc9 and/or SUMO-1 in cell lines and cortical neurons protects against oxygen and glucose deprivation. To examine whether increased global SUMOylation protects...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Yang-ja, Mou, Yongshan, Maric, Dragan, Klimanis, Dace, Auh, Sungyoung, Hallenbeck, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189225/
https://www.ncbi.nlm.nih.gov/pubmed/22016779
http://dx.doi.org/10.1371/journal.pone.0025852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189225/
https://www.ncbi.nlm.nih.gov/pubmed/22016779
http://dx.doi.org/10.1371/journal.pone.0025852

Ejemplares similares