Mesenchymal Stem Cells Restore Frataxin Expression and Increase Hydrogen Peroxide Scavenging Enzymes in Friedreich Ataxia Fibroblasts

Dramatic advances in recent decades in understanding the genetics of Friedreich ataxia (FRDA)—a GAA triplet expansion causing greatly reduced expression of the mitochondrial protein frataxin—have thus far yielded no therapeutic dividend, since there remain no effective treatments that prevent or eve...

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Detalles Bibliográficos
Autores principales: Kemp, Kevin, Mallam, Elizabeth, Hares, Kelly, Witherick, Jonathan, Scolding, Neil, Wilkins, Alastair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189234/
https://www.ncbi.nlm.nih.gov/pubmed/22016819
http://dx.doi.org/10.1371/journal.pone.0026098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189234/
https://www.ncbi.nlm.nih.gov/pubmed/22016819
http://dx.doi.org/10.1371/journal.pone.0026098

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