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Effect of ABCB1 and ABCC3 Polymorphisms on Osteosarcoma Survival after Chemotherapy: A Pharmacogenetic Study

BACKGROUND: Standard treatment for osteosarcoma patients consists of a combination of cisplatin, adriamycin, and methotrexate before surgical resection of the primary tumour, followed by postoperative chemotherapy including vincristine and cyclophosphamide. Unfortunately, many patients still relapse...

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Detalles Bibliográficos
Autores principales: Caronia, Daniela, Patiño-Garcia, Ana, Peréz-Martínez, Antonio, Pita, Guillermo, Moreno, Leticia Tais, Zalacain-Díez, Marta, Molina, Blanca, Colmenero, Isabel, Sierrasesúmaga, Luis, Benítez, Javier, Gonzalez-Neira, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189235/
https://www.ncbi.nlm.nih.gov/pubmed/22016816
http://dx.doi.org/10.1371/journal.pone.0026091