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Apolipoprotein J/Clusterin in Human Erythrocytes Is Involved in the Molecular Process of Defected Material Disposal during Vesiculation

BACKGROUND: We have showed that secretory Apolipoprotein J/Clusterin (sCLU) is down-regulated in senescent, stressed or diseased red blood cells (RBCs). It was hypothesized that sCLU loss relates to RBCs vesiculation, a mechanism that removes erythrocyte membrane patches containing defective or pote...

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Detalles Bibliográficos
Autores principales: Antonelou, Marianna H., Kriebardis, Anastasios G., Stamoulis, Konstantinos E., Trougakos, Ioannis P., Papassideri, Issidora S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189238/
https://www.ncbi.nlm.nih.gov/pubmed/22016805
http://dx.doi.org/10.1371/journal.pone.0026033