c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

BACKGROUND: Autophagy is a dynamic catabolic process characterized by the formation of double membrane vacuoles termed autophagosomes. LC3, a homologue of yeast Atg8, takes part in autophagosome formation, but the exact regulation mechanism of LC3 still needs to be elucidated. METHODS: Ceramide-indu...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Li, DanDan, Wang, LinLin, Xia, LiangPing, Ma, JianGuo, Guan, Zhong, Feng, GongKan, Zhu, XiaoFeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189397/
https://www.ncbi.nlm.nih.gov/pubmed/21943220
http://dx.doi.org/10.1186/1479-5876-9-161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189397/
https://www.ncbi.nlm.nih.gov/pubmed/21943220
http://dx.doi.org/10.1186/1479-5876-9-161

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