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c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

BACKGROUND: Autophagy is a dynamic catabolic process characterized by the formation of double membrane vacuoles termed autophagosomes. LC3, a homologue of yeast Atg8, takes part in autophagosome formation, but the exact regulation mechanism of LC3 still needs to be elucidated. METHODS: Ceramide-indu...

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Detalles Bibliográficos
Autores principales:	Sun, Ting, Li, DanDan, Wang, LinLin, Xia, LiangPing, Ma, JianGuo, Guan, Zhong, Feng, GongKan, Zhu, XiaoFeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189397/ https://www.ncbi.nlm.nih.gov/pubmed/21943220 http://dx.doi.org/10.1186/1479-5876-9-161

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