Prediction of Enzyme Mutant Activity Using Computational Mutagenesis and Incremental Transduction

Wet laboratory mutagenesis to determine enzyme activity changes is expensive and time consuming. This paper expands on standard one-shot learning by proposing an incremental transductive method (T2bRF) for the prediction of enzyme mutant activity during mutagenesis using Delaunay tessellation and 4-...

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Detalles Bibliográficos
Autores principales: Basit, Nada, Wechsler, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189455/
https://www.ncbi.nlm.nih.gov/pubmed/22007208
http://dx.doi.org/10.1155/2011/958129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189455/
https://www.ncbi.nlm.nih.gov/pubmed/22007208
http://dx.doi.org/10.1155/2011/958129

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