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Cell Transformation and the Evolution of a Field of Precancerization As It Relates to Oral Leukoplakia
Potentially malignant oral leukoplakias arise within precancerized epithelial fields consisting of cytogenetically altered keratinocytes at various stages of transformation. The evolution of a clone of keratinocytes culminating in a precancerous phenotype is a function of the number of mutagenic eve...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189556/ https://www.ncbi.nlm.nih.gov/pubmed/22007217 http://dx.doi.org/10.1155/2011/321750 |