Investigation on Quantitative Structure Activity Relationships and Pharmacophore Modeling of a Series of mGluR2 Antagonists

MGluR2 is G protein-coupled receptor that is targeted for diseases like anxiety, depression, Parkinson’s disease and schizophrenia. Herein, we report the three-dimensional quantitative structure–activity relationship (3D-QSAR) studies of a series of 1,3-dihydrobenzo[ b][1,4]diazepin-2-one derivative...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Meng-Qi, Zhang, Xiao-Le, Li, Yan, Fan, Wen-Jia, Wang, Yong-Hua, Hao, Ming, Zhang, Shu-Wei, Ai, Chun-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189765/
https://www.ncbi.nlm.nih.gov/pubmed/22016641
http://dx.doi.org/10.3390/ijms12095999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189765/
https://www.ncbi.nlm.nih.gov/pubmed/22016641
http://dx.doi.org/10.3390/ijms12095999

Ejemplares similares