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Investigation on Quantitative Structure Activity Relationships and Pharmacophore Modeling of a Series of mGluR2 Antagonists
MGluR2 is G protein-coupled receptor that is targeted for diseases like anxiety, depression, Parkinson’s disease and schizophrenia. Herein, we report the three-dimensional quantitative structure–activity relationship (3D-QSAR) studies of a series of 1,3-dihydrobenzo[ b][1,4]diazepin-2-one derivative...
Autores principales: | Zhang, Meng-Qi, Zhang, Xiao-Le, Li, Yan, Fan, Wen-Jia, Wang, Yong-Hua, Hao, Ming, Zhang, Shu-Wei, Ai, Chun-Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189765/ https://www.ncbi.nlm.nih.gov/pubmed/22016641 http://dx.doi.org/10.3390/ijms12095999 |
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