Probing Structural Features and Binding Mode of 3-Arylpyrimidin-2,4-diones within Housefly γ-Aminobutyric Acid (GABA) Receptor

In order to obtain structural features of 3-arylpyrimidin-2,4-diones emerged as promising inhibitors of insect γ-aminobutyric acid (GABA) receptor, a set of ligand-/receptor-based 3D-QSAR models for 60 derivatives are generated using Comparative Molecular Field Analysis (CoMFA) and Comparative Molec...

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Detalles Bibliográficos
Autores principales: Li, Qinfan, Zhang, Lihui, Ma, Zhi, Kong, Xiangya, Wang, Fangfang, Zhang, Hong, Wang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189783/
https://www.ncbi.nlm.nih.gov/pubmed/22016659
http://dx.doi.org/10.3390/ijms12096293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189783/
https://www.ncbi.nlm.nih.gov/pubmed/22016659
http://dx.doi.org/10.3390/ijms12096293

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