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Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells

OBJECTIVE: Vascular smooth muscle cell (VSMC) hypertrophy and proliferation occur in response to strain-induced local and systemic inflammatory cytokines and growth factors which may contribute to hypertension, atherosclerosis, and restenosis. We hypothesize VSMC strain, modeling normotensive arteri...

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Detalles Bibliográficos
Autores principales: Schad, Joseph F, Meltzer, Kate R, Hicks, Michael R, Beutler, David S, Cao, Thanh V, Standley, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189867/
https://www.ncbi.nlm.nih.gov/pubmed/21929819
http://dx.doi.org/10.1186/2045-824X-3-21