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Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells
OBJECTIVE: Vascular smooth muscle cell (VSMC) hypertrophy and proliferation occur in response to strain-induced local and systemic inflammatory cytokines and growth factors which may contribute to hypertension, atherosclerosis, and restenosis. We hypothesize VSMC strain, modeling normotensive arteri...
Autores principales: | Schad, Joseph F, Meltzer, Kate R, Hicks, Michael R, Beutler, David S, Cao, Thanh V, Standley, Paul R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189867/ https://www.ncbi.nlm.nih.gov/pubmed/21929819 http://dx.doi.org/10.1186/2045-824X-3-21 |
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