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Extracellular ATP activates NFAT-dependent gene expression in neuronal PC12 cells via P2X receptors
BACKGROUND: Treatment of neuronal PC12 cells with ATP induces depolarisation and increases intracellular calcium levels via purinergic receptors. In many cell types, sustained elevation of intracellular calcium levels cause changes in gene expression via activation of the transcription factor NFAT (...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189881/ https://www.ncbi.nlm.nih.gov/pubmed/21943104 http://dx.doi.org/10.1186/1471-2202-12-90 |