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Applications of Site-Specific Labeling to Study HAMLET, a Tumoricidal Complex of α-Lactalbumin and Oleic Acid

BACKGROUND: Alpha-lactalbumin (α-LA) is a calcium-bound mammary gland-specific protein that is found in milk. This protein is a modulator of β1,4-galactosyltransferase enzyme, changing its acceptor specificity from N-acetyl-glucosamine to glucose, to produce lactose, milk's main carbohydrate. W...

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Detalles Bibliográficos
Autores principales: Mercer, Natalia, Ramakrishnan, Boopathy, Boeggeman, Elizabeth, Qasba, Pradman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189925/
https://www.ncbi.nlm.nih.gov/pubmed/22016817
http://dx.doi.org/10.1371/journal.pone.0026093