Benzyl Isothiocyanate Suppresses Pancreatic Tumor Angiogenesis and Invasion by Inhibiting HIF-α/VEGF/Rho-GTPases: Pivotal Role of STAT-3

Our previous studies have shown that benzyl isothiocyanate (BITC) suppresses pancreatic tumor growth by inhibiting STAT-3; however, the exact mechanism of tumor growth suppression was not clear. Here we evaluated the effects and mechanism of BITC on pancreatic tumor angiogenesis. Our results reveal...

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Detalles Bibliográficos
Autores principales: Boreddy, Srinivas Reddy, Sahu, Ravi P., Srivastava, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189946/
https://www.ncbi.nlm.nih.gov/pubmed/22016776
http://dx.doi.org/10.1371/journal.pone.0025799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189946/
https://www.ncbi.nlm.nih.gov/pubmed/22016776
http://dx.doi.org/10.1371/journal.pone.0025799

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