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Gnarled-Trunk Evolutionary Model of Influenza A Virus Hemagglutinin

Human influenza A viruses undergo antigenic changes with gradual accumulation of amino acid substitutions on the hemagglutinin (HA) molecule. A strong antigenic mismatch between vaccine and epidemic strains often requires the replacement of influenza vaccines worldwide. To establish a practical mode...

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Detalles Bibliográficos
Autores principales: Ito, Kimihito, Igarashi, Manabu, Miyazaki, Yutaka, Murakami, Teiji, Iida, Syaka, Kida, Hiroshi, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189952/
https://www.ncbi.nlm.nih.gov/pubmed/22028800
http://dx.doi.org/10.1371/journal.pone.0025953