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A Mild Impairment of Mitochondrial Electron Transport Has Sex-Specific Effects on Lifespan and Aging in Mice

Impairments of various aspects of mitochondrial function have been associated with increased lifespan in various model organisms ranging from Caenorhabditis elegans to mice. For example, disruption of the function of the ‘Rieske’ iron-sulfur protein (RISP) of complex III of the mitochondrial electro...

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Detalles Bibliográficos
Autores principales: Hughes, Bryan G., Hekimi, Siegfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189954/
https://www.ncbi.nlm.nih.gov/pubmed/22028811
http://dx.doi.org/10.1371/journal.pone.0026116