Joint Binding of OTX2 and MYC in Promotor Regions Is Associated with High Gene Expression in Medulloblastoma

Both OTX2 and MYC are important oncogenes in medulloblastoma, the most common malignant brain tumor in childhood. Much is known about MYC binding to promoter regions, but OTX2 binding is hardly investigated. We used ChIP-on-chip data to analyze the binding patterns of both transcription factors in D...

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Detalles Bibliográficos
Autores principales: Bunt, Jens, Hasselt, Nancy E., Zwijnenburg, Danny A., Koster, Jan, Versteeg, Rogier, Kool, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189962/
https://www.ncbi.nlm.nih.gov/pubmed/22016811
http://dx.doi.org/10.1371/journal.pone.0026058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189962/
https://www.ncbi.nlm.nih.gov/pubmed/22016811
http://dx.doi.org/10.1371/journal.pone.0026058

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