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Association of Reactive Oxygen Species-Mediated Signal Transduction with In Vitro Apoptosis Sensitivity in Chronic Lymphocytic Leukemia B Cells

BACKGROUND: Chronic lymphocytic leukemia (CLL) is a B cell malignancy with a variable clinical course and unpredictable response to therapeutic agents. Single cell network profiling (SCNP) utilizing flow cytometry measures alterations in signaling biology in the context of molecular changes occurrin...

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Detalles Bibliográficos
Autores principales: Palazzo, Adam L., Evensen, Erik, Huang, Ying-Wen, Cesano, Alessandra, Nolan, Garry P., Fantl, Wendy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189964/
https://www.ncbi.nlm.nih.gov/pubmed/22016760
http://dx.doi.org/10.1371/journal.pone.0024592