The Rad50 Coiled Coil Domain is indispensable for Mre11 complex functions

The Mre11 complex (Mre11, Rad50, Xrs2 in S. cerevisiae) influences diverse functions in the DNA damage response. The complex comprises the globular DNA binding domain and the Rad50 hook domain which are linked by a long and extended Rad50 coiled coil domain. In this study, rad50 alleles encoding tru...

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Detalles Bibliográficos
Autores principales: Hohl, Marcel, Kwon, Youngho, Galván, Sandra Muñoz, Xue, Xiaoyu, Tous, Cristina, Aguilera, Andrés, Sung, Patrick, Petrini, John H.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190017/
https://www.ncbi.nlm.nih.gov/pubmed/21892167
http://dx.doi.org/10.1038/nsmb.2116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190017/
https://www.ncbi.nlm.nih.gov/pubmed/21892167
http://dx.doi.org/10.1038/nsmb.2116

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