Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin

Heterochromatin assembly at fission yeast centromeres involves a self-reinforcing loop mechanism wherein chromatin-bound RNAi factors facilitate targeting of Clr4–Rik1 methyltransferase. However, the initial nucleation of heterochromatin has remained elusive. We show that cells lacking Mlo3, a prote...

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Detalles Bibliográficos
Autores principales: Reyes-Turcu, Francisca E., Zhang, Ke, Zofall, Martin, Chen, Eesin, Grewal, Shiv I. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190054/
https://www.ncbi.nlm.nih.gov/pubmed/21892171
http://dx.doi.org/10.1038/nsmb.2122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190054/
https://www.ncbi.nlm.nih.gov/pubmed/21892171
http://dx.doi.org/10.1038/nsmb.2122

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