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Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin
Heterochromatin assembly at fission yeast centromeres involves a self-reinforcing loop mechanism wherein chromatin-bound RNAi factors facilitate targeting of Clr4–Rik1 methyltransferase. However, the initial nucleation of heterochromatin has remained elusive. We show that cells lacking Mlo3, a prote...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190054/ https://www.ncbi.nlm.nih.gov/pubmed/21892171 http://dx.doi.org/10.1038/nsmb.2122 |