Competition between ADAR and RNAi pathways for an extensive class of RNA targets

Adenosine deaminases that act on RNAs (ADARs) interact with double-stranded RNAs, deaminating adenosines to inosines. Previous studies of Caenorhabditis elegans suggested an antagonistic interaction between ADAR and RNAi machineries, with ADAR defects suppressed upon additional knockout of RNAi. The...

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Detalles Bibliográficos
Autores principales: Wu, Diane, Lamm, Ayelet T., Fire, Andrew Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190075/
https://www.ncbi.nlm.nih.gov/pubmed/21909095
http://dx.doi.org/10.1038/nsmb.2129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190075/
https://www.ncbi.nlm.nih.gov/pubmed/21909095
http://dx.doi.org/10.1038/nsmb.2129

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