Cargando…

Competition between ADAR and RNAi pathways for an extensive class of RNA targets

Adenosine deaminases that act on RNAs (ADARs) interact with double-stranded RNAs, deaminating adenosines to inosines. Previous studies of Caenorhabditis elegans suggested an antagonistic interaction between ADAR and RNAi machineries, with ADAR defects suppressed upon additional knockout of RNAi. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Diane, Lamm, Ayelet T., Fire, Andrew Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190075/ https://www.ncbi.nlm.nih.gov/pubmed/21909095 http://dx.doi.org/10.1038/nsmb.2129

Ejemplares similares

A rADAR defense against RNAi
por: Pasquinelli, Amy E.
Publicado: (2018)

Processing of Alu small RNAs by DICER/ADAR1 complexes and their RNAi targets
por: Shiromoto, Yusuke, et al.
Publicado: (2020)

C. elegans ADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway
por: Reich, Daniel P., et al.
Publicado: (2018)

Genetic Determinants of RNA Editing Levels of ADAR Targets in Drosophila melanogaster
por: Kurmangaliyev, Yerbol Z., et al.
Publicado: (2015)

Editing independent effects of ADARs on the miRNA/siRNA pathways
por: Heale, Bret S E, et al.
Publicado: (2009)

Effects of ADARs on small RNA processing pathways in C. elegans
por: Warf, M. Bryan, et al.
Publicado: (2012)

Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
por: Fischer, Sylvia E. J., et al.
Publicado: (2020)

Promoting RNA editing by ADAR attraction
por: Danan-Gotthold, Miri, et al.
Publicado: (2017)

ADAR RNA editing below the backbone
por: Keegan, Liam, et al.
Publicado: (2017)

ADAR Mediated RNA Editing Modulates MicroRNA Targeting in Human Breast Cancer
por: Roberts, Justin T., et al.
Publicado: (2018)

Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects
por: Keegan, Liam P., et al.
Publicado: (2011)

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure
por: Solomon, Oz, et al.
Publicado: (2017)

Right on target: The next class of efficient, safe, and specific RNAi triggers
por: Becker, Jonas, et al.
Publicado: (2022)

Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes
por: Keegan, Liam P, et al.
Publicado: (2004)

Genomic Analysis of ADAR1 Binding and its Involvement in Multiple RNA Processing Pathways
por: Bahn, Jae Hoon, et al.
Publicado: (2015)

The ADAR protein family
por: Savva, Yiannis A, et al.
Publicado: (2012)

Predicting sites of ADAR editing in double-stranded RNA
por: Eggington, Julie M., et al.
Publicado: (2011)

Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2
por: Phelps, Kelly J., et al.
Publicado: (2015)

The origin of the ADAR gene family and animal RNA editing
por: Grice, Laura F, et al.
Publicado: (2015)

RNA Editing, ADAR1, and the Innate Immune Response
por: Wang, Qingde, et al.
Publicado: (2017)

Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs
por: Walkley, Carl R., et al.
Publicado: (2017)

The ADAR1 editome reveals drivers of editing-specificity for ADAR1-isoforms
por: Kleinova, Renata, et al.
Publicado: (2023)

ADAR1- and ADAR2-mediated regulation of maturation and targeting of miR-376b to modulate GABA neurotransmitter catabolism
por: Widmark, Albin, et al.
Publicado: (2022)

The Interplay between RNA Editing Regulator ADAR1 and Immune Environment in Colorectal Cancer
por: Zheng, Guo-Liang, et al.
Publicado: (2023)

Evaluation of the Interplay between the ADAR Editome and Immunotherapy in Melanoma
por: Tusup, Marina, et al.
Publicado: (2021)

Asian Citrus Psyllid RNAi Pathway – RNAi evidence
por: Taning, Clauvis N. T., et al.
Publicado: (2016)

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis
por: Deffit, Sarah N, et al.
Publicado: (2017)

Modulation of ADAR1 editing activity by Z-RNA in vitro
por: Koeris, Michael, et al.
Publicado: (2005)

ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression
por: Wang, Isabel X., et al.
Publicado: (2013)

Complex regulation of ADAR-mediated RNA-editing across tissues
por: Huntley, Melanie A., et al.
Publicado: (2016)

ADAR1 and MicroRNA; A Hidden Crosstalk in Cancer
por: Cho, Charles J., et al.
Publicado: (2017)

Novel Engineered Programmable Systems for ADAR-Mediated RNA Editing
por: Aquino-Jarquin, Guillermo
Publicado: (2020)

Deciphering the Biological Significance of ADAR1–Z-RNA Interactions
por: Nakahama, Taisuke, et al.
Publicado: (2021)

ADAR1-Mediated RNA Editing and Its Role in Cancer
por: Liu, Jizhe, et al.
Publicado: (2022)

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
por: Mannion, Niamh M., et al.
Publicado: (2014)

ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway
por: Guo, Xinfeng, et al.
Publicado: (2021)

Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1(p150)
por: Pfaller, Christian K., et al.
Publicado: (2018)

The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster
por: Li, Xianghua, et al.
Publicado: (2014)

New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins
por: Mannion, Niamh, et al.
Publicado: (2015)

Profiling the RNA editomes of wild-type C. elegans and ADAR mutants
por: Zhao, Han-Qing, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7ab6fukfl7loip1j5rviq1o6ep