Assessing the pathological relevance of SPINK1 promoter variants

The SPINK1 gene, encoding the human pancreatic secretory trypsin inhibitor, is one of the major genes involved in predisposition to chronic pancreatitis (CP). In this study we have assessed the potential functional impact of 11 SPINK1 promoter variants by means of both luciferase reporter gene assay...

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Detalles Bibliográficos
Autores principales: Boulling, Arnaud, Witt, Heiko, Chandak, Giriraj Ratan, Masson, Emmanuelle, Paliwal, Sumit, Bhaskar, Seema, Reddy, D Nageshwar, Cooper, David N, Chen, Jian-Min, Férec, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190254/
https://www.ncbi.nlm.nih.gov/pubmed/21610753
http://dx.doi.org/10.1038/ejhg.2011.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190254/
https://www.ncbi.nlm.nih.gov/pubmed/21610753
http://dx.doi.org/10.1038/ejhg.2011.79

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