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Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest

BACKGROUND: Metaphase cells have short spindles for efficient bi-orientation of chromosomes. The cohesin proteins hold sister chromatids together, creating Sister Chromatid Cohesion (SCC) that helps in the maintenance of short spindle lengths in metaphase. The budding yeast protein Chl1p, which has...

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Detalles Bibliográficos
Autores principales: Laha, Suparna, Das, Shankar P, Hajra, Sujata, Sanyal, Kaustuv, Sinha, Pratima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190345/
https://www.ncbi.nlm.nih.gov/pubmed/21943249
http://dx.doi.org/10.1186/1471-2156-12-83