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Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons

BACKGROUND: Voltage-gated sodium channels play key roles in acute and chronic pain processing. The molecular, biophysical, and pharmacological properties of sodium channel currents have been extensively studied for peripheral nociceptors while the properties of sodium channel currents in dorsal horn...

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Detalles Bibliográficos
Autores principales: Hildebrand, Michael E, Mezeyova, Janette, Smith, Paula L, Salter, Michael W, Tringham, Elizabeth, Snutch, Terrance P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190347/
https://www.ncbi.nlm.nih.gov/pubmed/21910862
http://dx.doi.org/10.1186/1744-8069-7-67