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Transcriptional responses of Burkholderia cenocepacia to polymyxin B in isogenic strains with diverse polymyxin B resistance phenotypes

BACKGROUND: Burkholderia cenocepacia is a Gram-negative opportunistic pathogen displaying high resistance to antimicrobial peptides and polymyxins. We identified mechanisms of resistance by analyzing transcriptional changes to polymyxin B treatment in three isogenic B. cenocepacia strains with diver...

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Detalles Bibliográficos
Autores principales: Loutet, Slade A, Di Lorenzo, Flaviana, Clarke, Chelsea, Molinaro, Antonio, Valvano, Miguel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190405/
https://www.ncbi.nlm.nih.gov/pubmed/21955326
http://dx.doi.org/10.1186/1471-2164-12-472