ATP-Induced Helicase Slippage Reveals Highly Coordinated Subunits

Helicases are vital enzymes that carry out strand separation of duplex nucleic acids during replication, repair, and recombination(1,2). Bacteriophage T7 gene product 4 is a model hexameric helicase which has been observed to utilize dTTP, but not ATP, to unwind dsDNA as it translocates from 5′ to 3...

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Detalles Bibliográficos
Autores principales: Sun, Bo, Johnson, Daniel S., Patel, Gayatri, Smith, Benjamin Y., Pandey, Manjula, Patel, Smita S., Wang, Michelle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190587/
https://www.ncbi.nlm.nih.gov/pubmed/21927003
http://dx.doi.org/10.1038/nature10409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190587/
https://www.ncbi.nlm.nih.gov/pubmed/21927003
http://dx.doi.org/10.1038/nature10409

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