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ATP-Induced Helicase Slippage Reveals Highly Coordinated Subunits
Helicases are vital enzymes that carry out strand separation of duplex nucleic acids during replication, repair, and recombination(1,2). Bacteriophage T7 gene product 4 is a model hexameric helicase which has been observed to utilize dTTP, but not ATP, to unwind dsDNA as it translocates from 5′ to 3...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190587/ https://www.ncbi.nlm.nih.gov/pubmed/21927003 http://dx.doi.org/10.1038/nature10409 |