Cysteine Scanning Mutagenesis (Residues Glu(52)–Gly(96)) of the Human P2X1 Receptor for ATP: MAPPING AGONIST BINDING AND CHANNEL GATING

P2X receptors are ATP-gated cation channels. The x-ray structure of a P2X4 receptor provided a major advance in understanding the molecular basis of receptor properties. However, how agonists are coordinated, the extent of the binding site, and the contribution of the vestibules in the extracellular...

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Detalles Bibliográficos
Autores principales: Allsopp, Rebecca C., El Ajouz, Sam, Schmid, Ralf, Evans, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190727/
https://www.ncbi.nlm.nih.gov/pubmed/21690089
http://dx.doi.org/10.1074/jbc.M111.260364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190727/
https://www.ncbi.nlm.nih.gov/pubmed/21690089
http://dx.doi.org/10.1074/jbc.M111.260364

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