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Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein from Enterococcus faecalis and Crystal Structure of the Activator-Substrate Complex

The EF1143 protein from Enterococcus faecalis is a distant homolog of deoxynucleotide triphosphate triphosphohydrolases (dNTPases) from Escherichia coli and Thermus thermophilus. These dNTPases are important components in the regulation of the dNTP pool in bacteria. Biochemical assays of the EF1143...

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Detalles Bibliográficos
Autores principales: Vorontsov, Ivan I., Minasov, George, Kiryukhina, Olga, Brunzelle, Joseph S., Shuvalova, Ludmilla, Anderson, Wayne F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190883/
https://www.ncbi.nlm.nih.gov/pubmed/21757692
http://dx.doi.org/10.1074/jbc.M111.250456