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Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever

BACKGROUND: Lassa and Junín viruses are the most prominent members of the Arenaviridae family of viruses that cause viral hemorrhagic fever syndromes Lassa fever and Argentine hemorrhagic fever, respectively. At present, ribavirin is the only antiviral drug indicated for use in treatment of these di...

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Detalles Bibliográficos
Autores principales: Mendenhall, Michelle, Russell, Andrew, Smee, Donald F., Hall, Jeffery O., Skirpstunas, Ramona, Furuta, Yousuke, Gowen, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191123/
https://www.ncbi.nlm.nih.gov/pubmed/22022624
http://dx.doi.org/10.1371/journal.pntd.0001342