Memory Phenotype CD4 T Cells Undergoing Rapid, Nonburst-Like, Cytokine-Driven Proliferation Can Be Distinguished from Antigen-Experienced Memory Cells

Memory phenotype (CD44(bright), CD25(negative)) CD4 spleen and lymph node T cells (MP cells) proliferate rapidly in normal or germ-free donors, with BrdU uptake rates of 6% to 10% per day and Ki-67 positivity of 18% to 35%. The rapid proliferation of MP cells stands in contrast to the much slower pr...

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Detalles Bibliográficos
Autores principales: Younes, Souheil-Antoine, Punkosdy, George, Caucheteux, Stephane, Chen, Tao, Grossman, Zvi, Paul, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191130/
https://www.ncbi.nlm.nih.gov/pubmed/22022231
http://dx.doi.org/10.1371/journal.pbio.1001171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191130/
https://www.ncbi.nlm.nih.gov/pubmed/22022231
http://dx.doi.org/10.1371/journal.pbio.1001171

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