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Altered Connectivity Pattern of Hubs in Default-Mode Network with Alzheimer's Disease: An Granger Causality Modeling Approach

BACKGROUND: Evidences from normal subjects suggest that the default-mode network (DMN) has posterior cingulate cortex (PCC), medial prefrontal cortex (MPFC) and inferior parietal cortex (IPC) as its hubs; meanwhile, these DMN nodes are often found to be abnormally recruited in Alzheimer's disea...

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Detalles Bibliográficos
Autores principales: Miao, Xiaoyan, Wu, Xia, Li, Rui, Chen, Kewei, Yao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191142/
https://www.ncbi.nlm.nih.gov/pubmed/22022410
http://dx.doi.org/10.1371/journal.pone.0025546