Self-Renewing Pten(-/-)TP53(-/-) Protospheres Produce Metastatic Adenocarcinoma Cell Lines with Multipotent Progenitor Activity

Prostate cancers of luminal adenocarcinoma histology display a range of clinical behaviors. Although most prostate cancers are slow-growing and indolent, a proportion is aggressive, developing metastasis and resistance to androgen deprivation treatment. One hypothesis is that a portion of aggressive...

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Detalles Bibliográficos
Autores principales: Abou-Kheir, Wassim, Hynes, Paul G., Martin, Philip, Yin, Juan Juan, Liu, Yen-Nien, Seng, Victoria, Lake, Ross, Spurrier, Joshua, Kelly, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191168/
https://www.ncbi.nlm.nih.gov/pubmed/22022528
http://dx.doi.org/10.1371/journal.pone.0026112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191168/
https://www.ncbi.nlm.nih.gov/pubmed/22022528
http://dx.doi.org/10.1371/journal.pone.0026112

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