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Expression and Localization of microRNAs in Perinatal Rat Pancreas: Role of miR-21 in Regulation of Cholesterol Metabolism

OBJECTIVE: To investigate the expression of pancreatic microRNAs (miRNAs) during the period of perinatal beta-cell expansion and maturation in rats, determine the localization of these miRNAs and perform a pathway analysis with predicted target mRNAs expressed in perinatal pancreas. RESEARCH DESIGN...

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Detalles Bibliográficos
Autores principales: Larsen, Louise, Rosenstierne, Maiken W., Gaarn, Louise W., Bagge, Annika, Pedersen, Lykke, Dahmcke, Christina M., Nielsen, Jens H., Dalgaard, Louise T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191174/
https://www.ncbi.nlm.nih.gov/pubmed/22022489
http://dx.doi.org/10.1371/journal.pone.0025997