Low Expression Of PP2A Regulatory Subunit B55α Is Associated With T308 Phosphorylation Of AKT And Shorter Complete Remission Duration In Acute Myeloid Leukemia Patients

The regulation of Protein Kinase B (AKT) is a dynamic process that depends on the balance between phosphorylation by upstream kinases for activation and inactivation by dephosphorylation by protein phosphatases. Phosphorylated AKT is commonly found in acute myeloid leukemia (AML) and confers an unfa...

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Detalles Bibliográficos
Autores principales: Ruvolo, Peter P., Qui, YiHua, Coombes, Kevin R., Zhang, Nianxiang, Ruvolo, Vivian R., Borthakur, Gautam, Konopleva, Marina, Andreeff, Michael, Kornblau, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191228/
https://www.ncbi.nlm.nih.gov/pubmed/21660042
http://dx.doi.org/10.1038/leu.2011.146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191228/
https://www.ncbi.nlm.nih.gov/pubmed/21660042
http://dx.doi.org/10.1038/leu.2011.146

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