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Quantitative characterization of fluorophores in multi-component nanoprobes by single-molecule fluorescence

Multi-modal nanoparticles incorporating fluorophores are increasingly being used for medical applications. The number of fluorophores incorporated into the nanoparticles during synthesis is stochastic, leaving some nanoparticles devoid of fluorophores. Determining the number, the brightness and the...

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Detalles Bibliográficos
Autores principales: Bumb, Ambika, Sarkar, Susanta K., Wu, Xufeng S., Brechbiel, Martin W., Neuman, Keir C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191443/
https://www.ncbi.nlm.nih.gov/pubmed/22025982
http://dx.doi.org/10.1364/BOE.2.002761