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Moderately delayed post-insult treatment with normobaric hyperoxia reduces excitotoxin-induced neuronal degeneration but increases ischemia-induced brain damage

BACKGROUND: The use and benefits of normobaric oxygen (NBO) in patients suffering acute ischemic stroke is still controversial. RESULTS: Here we show for the first time to the best of our knowledge that NBO reduces both NMDA-induced calcium influxes in vitro and NMDA-induced neuronal degeneration in...

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Detalles Bibliográficos
Autores principales: Haelewyn, Benoit, Chazalviel, Laurent, Nicole, Olivier, Lecocq, Myriam, Risso, Jean-Jacques, Abraini, Jacques H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191484/
https://www.ncbi.nlm.nih.gov/pubmed/22146487
http://dx.doi.org/10.1186/2045-9912-1-2