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RNA interference-mediated silencing of BACE and APP attenuates the isoflurane-induced caspase activation
BACKGROUND: β-Amyloid protein (Aβ) has been shown to potentiate the caspase-3 activation induced by the commonly used inhalation anesthetic isoflurane. However, it is unknown whether reduction in Aβ levels can attenuate the isoflurane-induced caspase-3 activation. We therefore set out to determine t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191487/ https://www.ncbi.nlm.nih.gov/pubmed/22146340 http://dx.doi.org/10.1186/2045-9912-1-5 |