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In vivo kinetics of transcription initiation of the lar promoter in Escherichia coli. Evidence for a sequential mechanism with two rate-limiting steps

BACKGROUND: In Escherichia coli the mean and cell-to-cell diversity in RNA numbers of different genes vary widely. This is likely due to different kinetics of transcription initiation, a complex process with multiple rate-limiting steps that affect RNA production. RESULTS: We measured the in vivo ki...

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Detalles Bibliográficos
Autores principales: Kandhavelu, Meenakshisundaram, Mannerström, Henrik, Gupta, Abhishekh, Häkkinen, Antti, Lloyd-Price, Jason, Yli-Harja, Olli, Ribeiro, Andre S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191489/
https://www.ncbi.nlm.nih.gov/pubmed/21943372
http://dx.doi.org/10.1186/1752-0509-5-149