Cargando…

In vivo kinetics of transcription initiation of the lar promoter in Escherichia coli. Evidence for a sequential mechanism with two rate-limiting steps

BACKGROUND: In Escherichia coli the mean and cell-to-cell diversity in RNA numbers of different genes vary widely. This is likely due to different kinetics of transcription initiation, a complex process with multiple rate-limiting steps that affect RNA production. RESULTS: We measured the in vivo ki...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kandhavelu, Meenakshisundaram, Mannerström, Henrik, Gupta, Abhishekh, Häkkinen, Antti, Lloyd-Price, Jason, Yli-Harja, Olli, Ribeiro, Andre S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191489/ https://www.ncbi.nlm.nih.gov/pubmed/21943372 http://dx.doi.org/10.1186/1752-0509-5-149

Ejemplares similares

Dynamics of transcription driven by the tetA promoter, one event at a time, in live Escherichia coli cells
por: Muthukrishnan, Anantha-Barathi, et al.
Publicado: (2012)

Inference of Kinetic Parameters of Delayed Stochastic Models of Gene Expression Using a Markov Chain Approximation
por: Mannerstrom, Henrik, et al.
Publicado: (2010)

Cell-to-cell diversity in protein levels of a gene driven by a tetracycline inducible promoter
por: Smolander, Olli-Pekka, et al.
Publicado: (2011)

Cell segmentation by multi-resolution analysis and maximum likelihood estimation (MAMLE)
por: Chowdhury, Sharif, et al.
Publicado: (2013)

In vivo single-molecule kinetics of activation and subsequent activity of the arabinose promoter
por: Mäkelä, Jarno, et al.
Publicado: (2013)

Effects of Rate-Limiting Steps in Transcription Initiation on Genetic Filter Motifs
por: Häkkinen, Antti, et al.
Publicado: (2013)

Anticancer activity of THMPP: Downregulation of PI3K/ S6K1 in breast cancer cell line
por: Palanivel, Suresh, et al.
Publicado: (2020)

Identifying the miRNA Signature Association with Aging-Related Senescence in Glioblastoma
por: Gnanavel, Mutharasu, et al.
Publicado: (2021)

Origins of Transcriptional Transition: Balance between Upstream and Downstream Regulatory Gene Sequences
por: Sala, Adrien, et al.
Publicado: (2015)

Alkylaminophenol and GPR17 Agonist for Glioblastoma Therapy: A Combinational Approach for Enhanced Cell Death Activity
por: Doan, Phuong, et al.
Publicado: (2021)

Programmed cell death detection methods: a systematic review and a categorical comparison
por: Kari, Sana, et al.
Publicado: (2022)

Alkylaminophenol Induces G1/S Phase Cell Cycle Arrest in Glioblastoma Cells Through p53 and Cyclin-Dependent Kinase Signaling Pathway
por: Doan, Phuong, et al.
Publicado: (2019)

P2Y1 agonist HIC in combination with androgen receptor inhibitor abiraterone acetate impairs cell growth of prostate cancer
por: Le, Hien Thi Thu, et al.
Publicado: (2022)

Effects of Transcriptional Pausing on Gene Expression Dynamics
por: Rajala, Tiina, et al.
Publicado: (2010)

Effects of multimerization on the temporal variability of protein complex abundance
por: Häkkinen, Antti, et al.
Publicado: (2013)

Temperature-Dependent Model of Multi-step Transcription Initiation in Escherichia coli Based on Live Single-Cell Measurements
por: Oliveira, Samuel M. D., et al.
Publicado: (2016)

Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent
por: Le, Hien Thi Thu, et al.
Publicado: (2019)

Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment
por: Nguyen, Phung, et al.
Publicado: (2021)

In silico analysis of division times of Escherichia coli populations as a function of the partitioning scheme of non-functional proteins
por: Gupta, Abhishekh, et al.
Publicado: (2015)

Stochastic sequence-level model of coupled transcription and translation in prokaryotes
por: Mäkelä, Jarno, et al.
Publicado: (2011)

Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol through the Modulation of EGFR and CSC Signaling Pathways
por: Doan, Phuong, et al.
Publicado: (2020)

Cancer research in the era of next-generation sequencing and big data calls for intelligent modeling
por: Yli-Hietanen, Jari, et al.
Publicado: (2015)

Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)
por: Viswanathan, Anisha, et al.
Publicado: (2019)

Erratum: Viswanathan, A., et al. Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation). Cells 2019, 8, 1624
por: Viswanathan, Anisha, et al.
Publicado: (2020)

Dissecting the stochastic transcription initiation process in live Escherichia coli
por: Lloyd-Price, Jason, et al.
Publicado: (2016)

Targeting Orphan G Protein-Coupled Receptor 17 with T0 Ligand Impairs Glioblastoma Growth
por: Doan, Phuong, et al.
Publicado: (2021)

In vitro characterization of arylhydrazones of active methylene derivatives
por: Palanivel, Suresh, et al.
Publicado: (2018)

Stochastic Differential Equation Model for Cerebellar Granule Cell Excitability
por: Saarinen, Antti, et al.
Publicado: (2008)

sgnesR: An R package for simulating gene expression data from an underlying real gene network structure considering delay parameters
por: Tripathi, Shailesh, et al.
Publicado: (2017)

Characterization of aberrant pathways across human cancers
por: Ylipää, Antti, et al.
Publicado: (2013)

A systems biological approach to identify key transcription factors and their genomic neighborhoods in human sarcomas
por: Ylipää, Antti, et al.
Publicado: (2011)

Cancer systems biology: signal processing for cancer research
por: Yli-Harja, Olli, et al.
Publicado: (2011)

Information propagation within the Genetic Network of Saccharomyces cerevisiae
por: Chowdhury, Sharif, et al.
Publicado: (2010)

Lars Ahlfors : at the summit of mathematics
por: Lehto, Olli
Publicado: (2015)

What Is a Digital Twin? Experimental Design for a Data-Centric Machine Learning Perspective in Health
por: Emmert-Streib, Frank, et al.
Publicado: (2022)

Simulation of microarray data with realistic characteristics
por: Nykter, Matti, et al.
Publicado: (2006)

A protein–protein interaction guided method for competitive transcription factor binding improves target predictions
por: Laurila, Kirsti, et al.
Publicado: (2009)

The transcription factor network of E. coli steers global responses to shifts in RNAP concentration
por: L.B. Almeida, Bilena, et al.
Publicado: (2022)

RMBNToolbox: random models for biochemical networks
por: Aho, Tommi, et al.
Publicado: (2007)

In Vivo Transcription Kinetics of a Synthetic Gene Uninvolved in Stress-Response Pathways in Stressed Escherichia coli Cells
por: Muthukrishnan, Anantha-Barathi, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_v9vr20cn1e1q60p2usdpa7rg7k