Protective Effects of Peroxisome Proliferator-Activated Receptor-α Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes

This study investigates the effects and possible mechanism of an agonist of PPARα, Wy14643, on primary hepatocytes subjected to H/R injury in rats. H/R induced a significant increase ALT, AST, MDA in the culture medium and ROS in the hepatocytes. These effects were reversed by pretreatment with Wy14...

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Detalles Bibliográficos
Autores principales: Chen, Ke, Li, Yuan-Hai, Xu, Si-Qi, Hu, Sheng-Hong, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191773/
https://www.ncbi.nlm.nih.gov/pubmed/22007188
http://dx.doi.org/10.1155/2012/547980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191773/
https://www.ncbi.nlm.nih.gov/pubmed/22007188
http://dx.doi.org/10.1155/2012/547980

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